Spontaneous neurological improvement in anti-Hu associated encephalomyelitis.
Open Access
- 1 March 1997
- journal article
- case report
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 62 (3) , 276-278
- https://doi.org/10.1136/jnnp.62.3.276
Abstract
Symptoms of anti-Hu associated paraneoplastic encephalomyelitis (PEM) and sensory neuropathy (PSN) are usually severe and irreversible. Two patients are reported whose symptoms improved spontaneously, and in one of them they resolved after resection of an inflammatory lesion of the lung. Spontaneous neurological improvement, although rare, should be considered in the evaluation of therapies for PEM/PSN.Keywords
This publication has 16 references indexed in Scilit:
- Pitfalls in the diagnosis of autoantibodies associated with paraneoplastic neurologic diseaseNeurology, 1996
- Intravenous immunoglobulin treatment in paraneoplastic neurological syndromes with antineuronal autoantibodies.Journal of Neurology, Neurosurgery & Psychiatry, 1996
- Hu antigens: Reactivity with hu antibodies, tumor expression, and major immunogenic sitesAnnals of Neurology, 1995
- Major histocompatibility proteins, anti-Hu antibodies, and paraneoplastic encephalomyelitis in neuroblastoma and small cell lung cancerCancer, 1995
- Indolent anti‐Hu‐associated paraneoplastic sensory neuropathyNeurology, 1994
- Regression of small-cell lung carcinoma in patients with paraneoplastic neuronal antibodiesThe Lancet, 1993
- Plasmapheresis and antineoplastic treatment in CNS paraneoplastic syndromes with antineuronal autoantibodiesNeurology, 1992
- Anti-Hu-Associated Paraneoplastic Encephalomyelitis/Sensory Neuronopathy A Clinical Study of 71 PatientsMedicine, 1992
- Detection of the anti‐Hu antibody in the serum of patients with small cell lung cancer—A quantitative western blot analysisAnnals of Neurology, 1990
- Autoantibodies in paraneoplastic syndromes associated with small‐cell lung cancerNeurology, 1988