Uterine rupture during induction of labor at term with intravaginal misoprostol
- 9 July 2001
- journal article
- case report
- Published by Wolters Kluwer Health
- Vol. 89 (5) , 832-833
- https://doi.org/10.1016/s0029-7844(97)00036-7
Abstract
Background: Misoprostol (prostaglandin E1) compares favorably with dinoprostone (prostaglandin E2) and oxytocin for labor induction at term. Excessive uterine activity has been reported using high-dose regimens, but no negative effect on outcomes has been observed. Case: Labor was induced in a 34-year-old multipara at 39 weeks' gestation using intravaginal misoprostol tablets. Five hours after administration of the second 25-μg dose, fetal bradycardia prompted emergency cesarean delivery. Hysterectomy and left salpingo-oophorectomy were necessary to control bleeding from a 15-cm posterior uterine wall rupture. Conclusion: Misoprostol can cause excessive uterine activity and uterine rupture.Keywords
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