THE MEASUREMENT AND METABOLISM OF THIAMIN AND OF A PYRIMIDINE STIMULATING YEAST FERMENTATION FOUND IN THE BLOOD CELLS AND URINE OF NORMAL INDIVIDUALS 1

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Abstract
Methods for the detn. of thiamin and the pyrimidine accelerator of yeast fermentation (PAYF) have been Actapted for application to the white cells and erythrocytes of normal individuals. The thiamin conc. of the leukocytes and platelets is about 10 times that of the erythrocytes, probably reflecting the respiratory activity of the white blood cells. The white blood cell levels of thiamin reflect thiamin deficiency and saturation of the body. White cells do not differ in their capacity to absorb thiamin, but can absorb only a limited, maximum amt. In the course of this metabolic activity, thiamin is probably broken down to PAYF.

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