THE PROPERDIN SYSTEM AND IMMUNITY
Open Access
- 1 July 1957
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 106 (1) , 99-110
- https://doi.org/10.1084/jem.106.1.99
Abstract
High molecular weight polysaccharide complexes derived from normal and neoplastic mammalian tissues were found to combine with properdin and to inactivate C'3 in vitro. These polysaccharide preparations were also found to alter properdin levels and non-specific resistance to Gram-negative infection in mice. In these manifestations, the tissue polysaccharides bore a marked resemblance to bacterial lipopolysaccharides.Keywords
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