Phenylpyruvic Acid as a Possible Precursor of o -Hydroxyphenylacetic Acid in Man
- 5 June 1959
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 129 (3362) , 1553
- https://doi.org/10.1126/science.129.3362.1553
Abstract
The oral administration of phenylpyruvic acid to human subjects results in increased urinary excretion of o-hydroxyphenylacetic acid. This demonstrates that phenylpyruvic acid may act as a precursor for o-hydroxy derivatives of phenylalanine and suggests that the formation of o-tyrosine is not necessary to account for the excretion of o-hydroxyphenylacetic acid in phenylketonuria.Keywords
This publication has 6 references indexed in Scilit:
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