In Utero Exposures and Breast Cancer: a Study of Opposite-Sexed Twins
Open Access
- 3 January 2001
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 93 (1) , 60-62
- https://doi.org/10.1093/jnci/93.1.60
Abstract
It has been suggested that hormonal exposures in utero influence the risk of breast cancer later in life (1). Estrogens are well-established risk factors for breast cancer (2), and there is a pronounced association between birthweight and antenatal estrogen exposure (3). Several epidemiologic studies (4–6) have found that preeclampsia, a perinatal event characterized by low maternal estrogen levels, is associated with a decreased risk of breast cancer, but the results in different studies (6–8) of the association between birthweight and breast cancer risk are not entirely consistent.Keywords
This publication has 22 references indexed in Scilit:
- Maternal Pregnancy Estriol Levels in Relation to Anamnestic and Fetal Anthropometric DataEpidemiology, 2000
- Maternal factors and breast cancer risk among young womenPaediatric and Perinatal Epidemiology, 1998
- Intrauterine Environment and Breast Cancer Risk in Women: A Population-Based StudyJNCI Journal of the National Cancer Institute, 1997
- Birthweight as a risk factor for breast cancerThe Lancet, 1996
- Perinatal Factors and Risk of Breast CancerEpidemiology, 1996
- Epidemiology of breast cancerEuropean Journal Of Cancer Prevention, 1995
- Evidence of prenatal influences on breast cancer riskThe Lancet, 1992
- Hypothesis: does breast cancer originate in utero?The Lancet, 1990
- Human Placental Lactogen and dU-Estrogen Levels in Normal Twin PregnanciesActa geneticae medicae et gemellologiae: twin research, 1985
- URINARY OESTRIOL EXCRETION IN TWIN PREGNANCIESBJOG: An International Journal of Obstetrics and Gynaecology, 1974