K-13, a novel inhibitor of angiotensin I converting enzyme produced by Micromonospora halophytica subsp. exilisia. II Structure determination.
- 1 January 1987
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 40 (4) , 455-458
- https://doi.org/10.7164/antibiotics.40.455
Abstract
The structure of K-13, a potent inhibitor of angiotensin I converting enzyme (ACE), was determined to be a cyclic dipeptide composed of tryosine and an unusual diamino dicarboxylic acid, isodityrosine, by spectral and chemical studies of K-13 and its derivatives.This publication has 3 references indexed in Scilit:
- K-13, a novel inhibitor of angiotensin I converting enzyme produced by Micromonospora halophytica subsp. exilisia. I Fermentation, isolation and biological properties.The Journal of Antibiotics, 1987
- An intramolecular linkage involving isodityrosine in extensinPhytochemistry, 1984
- Isodityrosine, a new cross-linking amino acid from plant cell-wall glycoproteinBiochemical Journal, 1982