The GTPase superfamily: conserved structure and molecular mechanism
- 10 January 1991
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 349 (6305) , 117-127
- https://doi.org/10.1038/349117a0
Abstract
GTPases are conserved molecular switches, built according to a common structural design. Rapidly accruing knowledge of individual GTPases—crystal structures, biochemical properties, or results of molecular genetic experiments—support and generate hypotheses relating structure to function in other members of the diverse family of GTPases.Keywords
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