Effect of simultaneous administration of polychlorinated biphenyls and alkylbenzene sulfonic acid salt in rats
- 1 June 1975
- journal article
- Published by Springer Nature in Archives of Environmental Contamination and Toxicology
- Vol. 3 (2) , 115-131
- https://doi.org/10.1007/bf02220782
Abstract
Administration of PCB to rats resulted in an increase in liver weight, hypertrophy with foam-like changes in cytoplasm of individual liver cells, an increase in liver cholesterol levels, an increase in liver aniline hydroxylase activity and a decrease in liver Na-K-Mg-dependent ATPase activity. When ABS was simultaneously administered with PCB, most of the above-mentioned abnormalities were observed to increase and were dependent on administration time and dosage. Testicular abnormalities were observed only in rats on long term co-administration of PCB and ABS.Keywords
This publication has 24 references indexed in Scilit:
- Effect of polychlorinated biphenyls on hepatic microsomal enzymes in the ratToxicology and Applied Pharmacology, 1972
- Embryonic Mortality and Chromosomal Alterations Caused by Aroclor 1254 in Ring DovesEnvironmental Health Perspectives, 1972
- Sensitivity of Fish ATPases to Polychlorinated BiphenylsNature, 1971
- Two-year feeding and reproduction study in rats with linear alkylbenzene sulfonate (LAS)Toxicology and Applied Pharmacology, 1971
- Rasche und einfache Ultramikromethode zur Bestimmung der SerumcholinesteraseDeutsche Medizinische Wochenschrift (1946), 1966
- A Simplification of Kind and King's Method for Determination of Serum PhosphataseScandinavian Journal of Clinical and Laboratory Investigation, 1966
- Highly specific sodium-potassium-activated adenosine triphosphatase from various tissues of rabbitBiochemical and Biophysical Research Communications, 1965
- The colorimetric micro-determination of non-esterified fatty acids in plasmaClinica Chimica Acta; International Journal of Clinical Chemistry, 1964
- Über eine waschaktive Substanz auf Basis DodecylbenzolsulfonatFette, Seifen, Anstrichmittel, 1963
- Rapid incremental methods for the determination of serum iron and iron-binding capacityJournal of Clinical Pathology, 1961