Change of Oxygen Affinity of Hemoglobin in Different Conditions of Blood Preservation

Abstract
Changes in Hb function were least in CPD [citrate phosphate dextrose] blood [human] in plastic bags, and more extensive in ACD [acid citrate dextrose] blood in plastic bags, ACD packed red blood cells in plastic bags and ACD blood in glass bottles, respectively. These decreases are consistent with the changes of organic phosphates levels during storage found in earlier studies. When old erythrocytes were incubated with inosine, pyruvate and phosphate, defective O2 transport function was completely restored even after 7 wk storage in ACD.