Peripheral Nerve Segmental Demyelination Induced by Intraneural Diphtheria Toxin Injection

1 February 1974

journal article
research article
Published by American Medical Association (AMA) in Archives of Neurology

Vol. 30 (2) , 157-162
https://doi.org/10.1001/archneur.1974.00490320045006

Abstract

Muscle twitch tension is grossly defective when the rat sciatic nerve is stimulated at a site proximal to an area of segmental demyelination induced by intraneural diphtheria toxin injection. If hydrocortisone is administered systemically 24 or 4 hours before testing, the defect is lessened considerably.

Keywords

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