EFFECTS OF O-2 BREATHING ON RQ, BLOOD-FLOW, AND DEVELOPED TENSION IN IN SITU DOG MUSCLE

  • 1 January 1978
    • journal article
    • research article
    • Vol. 10  (3) , 167-170
Abstract
The .ovrhdot.VO2 [O2 uptake], .ovrhdot.VCO2 [CO2 output], RQ [respiratory quotient], blood flow and developed tension of in situ dog gastrocnemius muscle were studied during contractions at 2.5 tw/s for both normoxic and hyperoxic breathing conditions. .ovrhdot.VO2 and developed tension were not significantly altered by the breathing gas changes. CaO2 rose by 11% during O2 breathing. A significant decrease of 15% in muscle blood flow resulted in no significant change in O2 transport (CaO2 .RTM. .ovrhdot.Q [cardiac output]) to muscle comparing hyperoxia to normoxia. Hyperoxia resulted in a significant decrease in muscle .ovrhdot.VCO2 and RQ. The cause of the RQ change with breathing gas O2 content is not certain. Evidence is presented indicating that infused epinephrine and propranolol can effect the response.

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