Intestinal Absorption of Manganese: An in vitro Study
- 1 January 1993
- journal article
- research article
- Published by S. Karger AG in Annals of Nutrition and Metabolism
- Vol. 37 (6) , 289-294
- https://doi.org/10.1159/000177779
Abstract
Our work on isolated rat intestine aimed at studying the hypothesis that the intestinal transport of manganese was carrier-mediated and, consequently, subjected to saturation. Our results confirm this hypothesis, assessing the concentration of carrier saturation for manganese at 0.5 mM. As this concentration, which may determine self-limitation in the intestinal absorption of this metal, is much higher than the maximal allowed concentration of the EEC Standard (50 mg/l), food and water should be carefully monitored for their manganese content in order to avoid reaching toxic concentrations in blood and tissues.Keywords
This publication has 0 references indexed in Scilit: