Effects of Conjugated Equine Estrogen on Stroke in the Women’s Health Initiative

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Open Access

23 May 2006

journal article
research article
Published by Wolters Kluwer Health in Circulation

Vol. 113 (20) , 2425-2434
https://doi.org/10.1161/circulationaha.105.594077

Abstract

Background— The Women’s Health Initiative (WHI) Estrogen Alone trial assessed the balance of benefits and risks of hormone use in healthy postmenopausal women. The trial was stopped prematurely because there was no benefit for coronary heart disease and an increased risk of stroke. This report provides a thorough analysis of the stroke finding using the final results from the completed trial database.

Keywords

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