THE RÔLE OF THE TUBULE IN THE EXCRETION OF INORGANIC PHOSPHATES BY THE AMPHIBIAN KIDNEY

Publisher Website
Google Scholar
Abstract
Fluid was collected from various portions of single renal tubules in Necturus and frog. Its phosphate concn., compared with that of blood plasma, rises progressively as it passes through proximal and distal tubules towards the ureter. Reasons are advanced for the belief that, in both animals, this concn. is effected by the reabsorption of phosphate-free fluid rather than by the secretion of phosphate. The distal tubule plays a somewhat larger role than the proximal tubule in the process. Perfusion of single proximal tubules in Necturus indicates that phosphate may pass through them both in the direction blood to lumen a,nd lumen to blood. The proximal tubules of both animals are capable of actively reabsorbing phosphate. It is this reabsorption rather than a failure of glomerular filtration which accounts for the occasional finding of a bladder urine with phosphate concn. below that of blood plasma.

This publication has 2 references indexed in Scilit: