Erythrocyte Protoporphyrin Test for Occupational Lead Exposure

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Abstract
• Determination of erythrocyte protoporphyrin levels was performed in workers who are occupationally exposed to lead. The level of erythrocyte protoporphyrin was easily measured with microsamples of blood by utilizing a fluorescent assay. The log of erythrocyte protoporphyrin level was closely correlated to blood lead level (r=.72) in lead-exposed workers. The erythrocyte protoporphyrin test is especially useful in the detection of mild increases in blood lead concentration under conditions of occupational exposure.