Abstract
Vegetative bacterial [Streptococcus viridans] endocarditis on the prolapsing mitral valve can be diagnosed with an echocardiogram, and the response to therapy can be followed with this technique. A dense mass of fuzzy echoes was noted on the prolapsing posterior leaflet of an echocardiogram from a patient with endocarditis. Three months after initiation of antibiotic therapy [penicillin G, streptomycin sulfate, erythromycin], this mass of echoes had disappeared and was replaced by a dense linear echo, suggesting fibrosis of the part of the mitral valve that was infected previously. Persistence of echocardiographic evidence of endocarditis, despite negative blood cultures, may indicate persistence of the risk of peripheral embolization.

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