Sensory‐predominant, painful, idiopathic neuropathy: Inflammatory changes in sural nerves

Abstract
Sensory‐predominant, painful, idiopathic neuropathies are a common clinical problem. In this retrospective study of 11 patients with such a neuropathy, we found axonal loss in 9, with multifocal axonal loss in 4 patients; there were large perivascular mononuclear inflammatory infiltrates (>50 cells) in 4 and smaller infiltrates (10–20 cells) in 4. These findings suggest that some cases of this neuropathy may be due to autoimmune vasculopathy and therefore may respond to immunotherapy. © 2002 Wiley Periodicals, Inc. Muscle Nerve 26: 413–416, 2002