Zur Histopathologie der Niere bei akuter hämorrhagischer und chronisch rezidivierender Pankreatitis

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Abstract
The most frequent and remarkable finding in histological studies of 40 cases of acute hemorrhagic and of chronic recurrent pancreatitis was a PAS [paraaminosalicylic acid]-positive enlargement of the mesangium and of the capillary basement membranes of the glo-meruli. Pathogenesis is thought to be based on altered protein- and lipid metabolism. These glomerular alterations are considered to be the morphological determinants of clinical renal insufficiency (oliguria, anuria, uremia). They must be classified as glomerulonephroses, a term which is being replaced in the modern medical literature by membraneous glomerulonephritis, mainly based on the results of animal experimentation.

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