Genetic and transcriptional analysis of absA, an antibiotic gene cluster‐linked two‐component system that regulates multiple antibiotics in Streptomyces coelicolor
- 1 February 2001
- journal article
- research article
- Published by Wiley in Molecular Microbiology
- Vol. 39 (3) , 553-566
- https://doi.org/10.1046/j.1365-2958.2001.02240.x
Abstract
In Streptomyces coelicolor, the AbsA1–AbsA2 two‐component system regulates the expression of multiple antibiotic gene clusters. Here, we show that the response regulator encoded by the absA2 gene is ...Keywords
This publication has 41 references indexed in Scilit:
- Genetic suppression analysis of non-antibiotic-producing mutants of the Streptomyces coelicolor absA locusMicrobiology, 1999
- Response regulator output in bacterial chemotaxisThe EMBO Journal, 1998
- Taking a genetic scalpel to the Streptomyces colonyMicrobiology, 1998
- Physical identification of a chromosomal locus encoding biosynthetic genes for the lipopeptide calcium-dependent antibiotic (CDA) of Streptomyces coelicolor A3(2)Microbiology, 1998
- Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction systemJournal of Bacteriology, 1996
- Structure of the Escherichia coli Response Regulator NarL,Biochemistry, 1996
- The glucose kinase gene of Streptomyces coelicolor A3(2): its nucleotide sequence, transcriptional analysis and role in glucose repressionMolecular Microbiology, 1992
- Identification of Streptomyces coelicolor genes involved in regulation of antibiotic synthesisGene, 1992
- Cloning, disruption, and transcriptional analysis of three RNA polymerase sigma factor genes of Streptomyces coelicolor A3(2)Journal of Bacteriology, 1990
- Mutations in a new Streptomyces coelicolor locus which globally block antibiotic biosynthesis but not sporulationJournal of Bacteriology, 1990