Intracellular Concentration and Transmembrane Fluxes of Sodium and Potassium in Erythrocytes of White Normal Male Subjects With and Without a Family History of Hypertension

1 February 1984

journal article
Published by Wolters Kluwer Health in Journal Of Hypertension

Vol. 2 (1) , 25-30
https://doi.org/10.1097/00004872-198402000-00005

Abstract

Compared with white normal males without a family history of hypertension (n = 43), red blood cells of white normal males with such a family history (n = 17) had a higher (P less than 0.01) intracellular sodium concentration (8.07 +/- 0.30 versus 7.33 +/- 0.17 mmol/l cells). This could be at least partly due to their lower (P less than 0.001) frusemide-sensitive sodium efflux rate (250 +/- 19 versus 424 +/- 23 mumol/l cells/h). Also their ouabain-resistant 86Rb-uptake (0.81 +/- 0.06 versus 0.97 +/- 0.03 mumol/l cells/h) was lower (P less than 0.05). Potassium concentration in the red blood cells was similar in both groups.

Keywords

This publication has 0 references indexed in Scilit: