Red blood cell volume and distribution before and after bleed-out in the rat

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Abstract
The distribution of red blood cells in nine normal Nembutalized rats (323.2–415.0 gm body weight) was determined by the Cr51-labeled red blood cell technique. Microliters of red blood cells per total and per gram of tissue are reported for the testes, brain, intestine, kidney, heart-lung, spleen, liver, bone, muscle and skin. Values are also listed for the same organs and tissues determined after rapid bleed-out as found by Muelheims, Dellenback and Rawson. A comparison of these values shows that the liver, heart-lung and muscle contribute approximately 80% of all red blood cells removed in the hemorrhage. The skin, bone, kidney and intestine contribute as a group the remaining 20% with a negligible contribution from the testes and brain and no contribution from the spleen.

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