Failure of 5-Hydroxytryptophan to Stimulate Prolactin and Growth Hormone Secretion in Man

Abstract
The effect of 200 mg 5-hydroxytryptophan (5-HTP) on prolactin and growth hormone secretion in six normal subjects did not differ significantly from the effect of placebo alone. Therefore, 5-HTP would not be a useful provocative stimulus to study prolactin and growth hormone secretion in man. 1 Supported by a grant (MO1-RR-30) from the Clinical Research Center Branch, Division of Research Facilities and Resources, grants (AM-01324, 5 TI-AM-5074, AM-5620), from the National Institute of Arthritis, Metabolic, and Digestive Diseases, and a Clinical Investigatorship (2650-01) from the Durham Veterans Administration Hospital (JMF).

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