CREATINE IN IN RED-BLOOD-CELLS AND BLOOD-PLASMA OF ADULT-RATS FOLLOWING EXPOSURE TO HYPOXIA

  • 1 January 1980
    • journal article
    • research article
    • Vol. 39  (10) , 1021-1026
Abstract
Adult rats exposed to hypoxia showed a definite increase of creatine concentration in red cells and plasma. The rise in cell creatine 37 h after the beginning of hypoxia had disappeared 2 days after the end of hypoxia. This is explained by the expulsion of preformed reticulocytes from the bone marrow. The increase of plasma creatine is supposed to be due to hypoxic damage to the muscles which release creatine into the blood stream.