Prophylaxis for Persons in Contact with Patients Who Have Rabies

Abstract
To the Editor: The recent letter by Dr. John Hoffer1 raised the question of who, if anyone, should be treated after contact with a patient with rabies. The only well-documented cases of human-to-human transmission of rabies have occurred by corneal transplantation,2 , 3 but the more usual person-to-person contacts, such as those between saliva or other body fluids and open cuts, wounds, or mucous membranes, could theoretically result in rabies infection. These kinds of contacts have led to transmission of rabies from animals to human beings.4 5 6 7 8 The presence of infectious virus in human beings has been documented in saliva, respiratory secretions, cerebrospinal . . .

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