T‐Cell Subpopulations in Head and Neck Carcinoma

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Abstract
Peripheral blood T‐cell subpopulations were quantitated with monoclonal antibodies in a group of 27 patients with biopsy‐proved squamous cell carcinoma of the head and neck. Abnormal quantitative relationships between helper/inducer T cells (Th) and suppressor/cytotoxic T cells (Ts) were encountered in many patients. Short‐term follow‐up of these patients did not demonstrate a correlation between these immune parameters and clinical course. Longer follow‐up and expansion of the data base will be necessary before a determination can be made of the value of quantitative T‐cell subpopulation analysis relative to its use as a prognostic indicator in patients with head and neck cancer.