Metabolism of Oestradiol-17β by Intestinal Bacteria in Rats
- 1 January 1975
- journal article
- research article
- Published by S. Karger AG in Hormone Research
- Vol. 6 (5-6) , 366-371
- https://doi.org/10.1159/000178687
Abstract
In vitro experiments were carried out in which [4–14C]oestradiol-17β was incubated with a culture from caecal content from adult male rats at 37°C in an atmosphere of nitrogen. Oestrone was identified as the only certain metabolite. Other metabolites, if present, were quantitatively unimportant. The conversion of oestradiol-17β to oestrone was estimated to be 22–42 %.Keywords
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