Estimation of the compliance of the human pulmonary "venous" system from pulmonary artery wedge pressure tracings.

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Abstract
Compliance (.DELTA.V/.DELTA.P) of the human pulmonary venous system was estimated in 37 human subjects, from the pulmonary artery wedge (PAW) pressure tracings, using 2 equations. (.DELTA.V/.DELTA.P) slope = 0.4 .cntdot. k" .cntdot. SV/(v-d) given in the appendix, and k" = 0.075 .**GRAPHIC**. + 0.9 given under methods. The estimated compliance of the pulmonary venous system was about 7-15 ml (mmHg)-1 in the control group, the patients of aortic valve disease with physical capacity of Class I .apprx. III of the [New York Heart Association, USA] and the patients of mitral stenosis with physical capacity of Class I. These values were in good agreement with that estimated by Guyton, i.e., 10 ml (mmHg)-1. For the entire population of pure mitral stenosis (n = 16) compliance (.DELTA.V/EDP) of the pulmonary venous system could be related to the .**GRAPHIC**. pressure by a regression curve of .DELTA.V/.DELTA.P = 1/(0.0106 .**GRAPHIC**. - 0.0173). It was pointed out in the discussion that this method and a different one using pulmonary blood volume measurements and passive leg elevation, performed simultaneously in a patient gave fairly similar values of the compliance of the pulmonary venous system.

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