Zum Wirkungsmechanismus des Toxopyrimidins, II. Die toxischen Eigenschaften verschiedenerN-mono- und -dialkylierter Toxopyrimidine
- 1 January 1962
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 328 (Jahresband) , 220-225
- https://doi.org/10.1515/bchm2.1962.328.1.220
Abstract
A number of N-mono- and dialkyl toxopyrimidines were synthesised, and their toxicity and antivitamin Bg activity tested with a pure strain of white mice on a B6-free diet. There was a marked increase in toxicity in the order HN-i-propyl < HN-n-propyl < HNH < HN-methyl < HN-ethyl< N-dimethyl.Keywords
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