Determination of cytosolic ADP and AMP concentrations and the free energy of ATP hydrolysis in human muscle and brain tissues with 31P NMR spectroscopy
- 1 December 1991
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 22 (2) , 505-511
- https://doi.org/10.1002/mrm.1910220258
Abstract
Based on experimentally determined concentrations of PCr, Pi, ATP, and H+, the ADP and AMP concentrations and the free energy for the ATP hydrolysis in normal human brain and muscle were calculated assuming that the creatine kinase‐ and the myokinase‐catalyzed reactions were in equilibrium, accounting for changes in pH and free Mg2+ ion concentration. © 1991 Academic Press, Inc.Keywords
This publication has 26 references indexed in Scilit:
- Noninvasive quantitation of phosphorus metabolites in human tissue by NMR spectroscopyJournal of Magnetic Resonance (1969), 1989
- Image-selected in Vivo spectroscopy (ISIS). A new technique for spatially selective nmr spectroscopyJournal of Magnetic Resonance (1969), 1986
- MeetingProceedings of the International Society for Magnetic Resonance in Medicine, 1986
- NMR Studies of Intracellular Metal Ions in Intact Cells and TissuesAnnual Review of Biophysics and Bioengineering, 1984
- THE (Na++K+)‐ATPase: COUPLING OF THE REACTION WITH ATP TO THE REACTION WITH Na+ AND K+Annals of the New York Academy of Sciences, 1982
- ON THE MECHANISM OF ENERGY RELEASE, TRANSFER, AND UTILIZATION IN Na, K‐ATPase TRANSPORT WORK: OLD IDEAS AND NEW FINDINGSAnnals of the New York Academy of Sciences, 1982
- Coordination of magnesium with adenosine 5′-diphosphate and triphosphateBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1980
- Magnetic resonance studies of the interaction of divalent metal cations with 2,3-bisphosphoglycerateBiochemical and Biophysical Research Communications, 1978
- Thermodynamic Studies of the Formation and Ionization of the Magnesium(II) Complexes of ADP and ATP over the pH Range 5 to 91Journal of the American Chemical Society, 1966
- The Apparent Stability Constants of Ionic Complexes of Various Adenosine Phosphates with Divalent Cations1,2Journal of the American Chemical Society, 1956