Prompt and durable hematopoietic reconstitution by unrelated cord blood transplantation in a child with Fanconi anemia
- 1 April 2001
- journal article
- case report
- Published by Springer Nature in Bone Marrow Transplantation
- Vol. 27 (7) , 767-769
- https://doi.org/10.1038/sj.bmt.1702876
Abstract
We describe here the case of an 8-year-old girl with Fanconi anemia (FA) whose hematopoiesis was successfully restored by unrelated umbilical cord blood (UCB) transplantation. The patient became resistant to androgen therapy, and developed intracranial hemorrhage and dyserythropoiesis. Her hematopoietic recovery after the transplantation was excellent and a complete chimerism has been durably maintained. UCB should be considered as a stem cell source for transplantation when a patient with FA does not have an HLA-identical unaffected sibling donor.Keywords
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