Platelet Dysfunction in Patients with Vitamin B12 Deficiency
- 1 January 1979
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 61 (2) , 75-79
- https://doi.org/10.1159/000207635
Abstract
Ten cases of pernicious anemia were reported in which 6 had abnormal aggregation with epinephrine, 3 with fibrinogen, 2 with ADP and 2 with ristocetin. Five patients had thrombocytopenia and 3 of these had a prolongation of the bleeding time. These abnormalities were normalized after vitamin B12 treatment. After treatment, platelet size changed toward a smaller diameter, but platelet size, however, was not signivicantly different from the normal platelet size distribution.This publication has 1 reference indexed in Scilit:
- A Qualitative Platelet Defect in Severe Vitamin B12DeficiencyAnnals of Internal Medicine, 1973