N.m.r. studies of enzyme mechanism. Comparison of the crystal structure and solid state 13C and 15N n.m.r. spectra of a carboxypeptidase A complex with glycyl tyrosine

Abstract
It is shown that solid state n.m.r. spectroscopy can be used to determine the extent of cleavage of the scissile amide bond in glycyl tyrosine, a slow substrate for the enzyme carboxypeptidase A in the crystalline enzyme substrate complex.

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