The Ca2+/Cl− dependent L‐[3H]glutamate binding: a new receptor or a particular transport process?
- 17 September 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 175 (1) , 31-36
- https://doi.org/10.1016/0014-5793(84)80563-3
Abstract
Ca2+/Cl− increases the L-[3H]glutamate binding to rat brain synaptic membranes. It was suggested that Ca2+/Cl− expresses a new class of glutamate receptors. We report several lines of evidence suggesting that Ca2+/Cl− in fact favours a glutamate transport into membrane vesicles. This finding may serve to reconcile most of the discrepancies found in the literature on the glutamate binding and its pharmacology.Keywords
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