The Penetration and Metabolism of H3-Dimethoate in Insects1

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Abstract
The toxicity, penetration, and metabolism of dimethoate in the house fly, Musca domestica L.; American cockroach, Periplaneta americana (L.); Colorado potato beetle, Leptinotarsa decemlineata (Say); large milkweed bug, Oncopeltus fasciatus (Dallas) ; and house cricket, Acheta domesticus (L.), were examined. There were large variations in all these factors, including a 5-fold variation in net production of oxygen analog and a 100-fold difference in cholinesterase sensitivity. Differences in penetration were seen during the initial 30 min, but thereafter the speed was almost the same for all species. The highly sensitive house fly showed particularly rapid penetration, extensive production of oxygen analog, and sensitive cholinesterase. However, variations in these factors could not explain all the variations in toxicity to the 5 species.