Principles and Recent Advances in Human DNA Fingerprinting
- 1 January 1991
- book chapter
- Published by Springer Nature
- Vol. 58, 1-19
- https://doi.org/10.1007/978-3-0348-7312-3_1
Abstract
Since 1985, DNA typing systems have played an increasingly important role in many aspects of human genetics, most notably in forensic and legal medicine. This article reviews the development of multilocus and single locus minisatellite DNA probes, and more recently the use of PCR to amplify hypervariable DNA loci, as well as discussing the biological properties of the unstable regions of DNA which form the basis of almost all DNA fingerprinting systems.Keywords
This publication has 41 references indexed in Scilit:
- Systematic cloning of human minisatellites from ordered array charomid librariesGenomics, 1990
- A novel human DNA polymorphism resulting from transfer of DNA from chromosome 6 to chromosome 16Genomics, 1990
- Characterization of a highly unstable mouse minisatellite locus: Evidence for somatic mutation during early developmentGenomics, 1989
- Unequal crossingover between homologous chromosomes is not the major mechanism involved in the generation of new alleles at VNTR lociGenomics, 1989
- Analysis of DNA Fingerprinting Data in Cases of Disputed PaternityMathematical Medicine and Biology: A Journal of the IMA, 1989
- Analysis of somatic mutations at human minisatellite loci in tumors and cell linesGenomics, 1989
- Molecular characterization of a spontaneously generated new allele at a VNTR locus: No exchange of flanking DNA sequence*1Genomics, 1988
- The human tumour-associated epithelial mucins are coded by an expressed hypervariable gene locus PUMNature, 1987
- A Sequence in M13 Phage Detects Hypervariable Minisatellites in Human and Animal DNAScience, 1987
- Intraspecific nucleotide sequence variability surrounding the origin of replication in human mitochondrial DNAGene, 1983