Effect of growth hormone and hydrocortisone on the synthesis of rapidly labeled, high molecular weight, nuclear RNA in rat liver
- 1 February 1969
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry
- Vol. 47 (2) , 226-229
- https://doi.org/10.1139/o69-036
Abstract
The effects of growth hormone and hydrocortisone on the synthesis of rat liver RNA have been studied. Administration of growth hormone stimulated the incorporation of 14C-orotic acid into 45 S preribosomal nucleolar RNA, and had no effect on the 6–50 S polydisperse nuclear RNA of extra-nucleolar origin. On the other hand, hydrocortisone stimulated the synthesis of all types of nuclear RNA, but mainly that of the 18 S class of 6–50 S polydisperse nuclear RNA.Keywords
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