Detection of human herpesvirus‐8 DNA in oral ulcer tissues of HIV‐infected individuals
- 1 May 1997
- journal article
- Published by Wiley in Oral Diseases
- Vol. 3 (S1) , S133-S134
- https://doi.org/10.1111/j.1601-0825.1997.tb00345.x
Abstract
OBJECTIVE: To determine the frequency of detection of human herpesvirus‐8 (HHV‐8) in HIV‐related oral ulcers. DESIGN: Analysis of archived biopsy material. METHODS: Nested polymerase chain reaction of DNA extracts. RESULTS: HHV‐8 DNA was detected in six of 10 oral ulcers of HIV‐positive patients without oral Kaposi's sarcoma (KS) lesions and five of 11 oral KS lesions. The positive non‐KS samples were derived from various oral sites. CONCLUSIONS: In HIV‐positive people, HHV‐8 can infect oral tissues that are not affected by KS.Keywords
This publication has 7 references indexed in Scilit:
- Is Kaposi's-sarcoma-associated herpesvirus detectable in semen of HIV-infected homosexual men?The Lancet, 1995
- Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcomaThe Lancet, 1995
- Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease [see comments]Blood, 1995
- Detection of Herpesvirus-Like DNA Sequences in Kaposi's Sarcoma in Patients with and Those without HIV InfectionNew England Journal of Medicine, 1995
- Human herpesvirus-like nucleic acid in various forms of Kaposi's sarcomaThe Lancet, 1995
- Identification of Herpesvirus-Like DNA Sequences in AIDS-Sssociated Kaposi's SarcomaScience, 1994
- Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection?The Lancet, 1990