Cyclohexenyl and Cyclohexylidene Inhibitors of 3-Dehydroquinate Synthase: Active Site Interactions Relevant to Enzyme Mechanism and Inhibitor Design
- 1 August 1997
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 119 (33) , 7645-7653
- https://doi.org/10.1021/ja961771z
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Inhibitor Ionization as a Determinant of Binding to 3-Dehydroquinate SynthaseThe Journal of Organic Chemistry, 1996
- Butane 2,3-Bisacetal Protection of Vicinal Diequatorial DiolsThe Journal of Organic Chemistry, 1996
- Divergence between the enzyme-catalyzed and noncatalyzed synthesis of 3-dehydroquinateThe Journal of Organic Chemistry, 1994
- Dehydroquinate synthase: the use of substrate analogs to probe the late steps of the catalyzed reactionBiochemistry, 1989
- Dehydroquinate synthase: the use of substrate analogs to probe the early steps of the catalyzed reactionBiochemistry, 1989
- Dehydroquinate synthase: a sheep in wolf's clothing?Journal of the American Chemical Society, 1989
- Does dehydroquinate synthase synthesize dehydroquinate?Journal of the American Chemical Society, 1988
- Stereochemical course of the cryptic elimination and cyclization steps in the reaction catalyzed by dehydroquinate synthaseJournal of the American Chemical Society, 1987
- Carbonyl methylenation of easily enolizable ketonesTetrahedron Letters, 1985
- Regiospecific addition of benzeneselenenyl halide to 1,1-dis ubstituted olefinsCanadian Journal of Chemistry, 1982