Juvenile Hormone Effects on Metamorphosis and Reproduction of the Fire Ant, Solenopsis invicta12

Abstract
Two juvenile hormone mimics, ZR 512 (ethyl 3, 7, 11-trimethyl-dodeca-2,4-dienoate) and ZR 515 (isopropyl 11-methoxy-3, 7, 11-trimethyl-dodeca-2,4-dienoate), were found to prevent larval metamorphosis and the production of larval broods, when 1 mg weekly + 100 ppm ad libitum were fed to colonies of the fire ant. Lower doses of 1 and 10 ppm (+ 10 or 100 μg weekly respectively) did not prevent reproduction or metamorphosis but caused a shift in the castes produced from all workers to a proportion of alate males. Filter paper impregnated with 5–10 ppm ZR 512 in small cups caused death of workers within 48 h, and caused aggressive behavior among workers exposed to it outside the colony. No such behavioral effects were noted with ZR 515.

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