A Convenient Synthesis of Versatile Side-chain Intermediates for Carbapenem Antibiotics
- 1 June 1995
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1995 (SI) , 575-577
- https://doi.org/10.1055/s-1995-5268
Abstract
A useful synthesis of (2S, 4S)-4-(4-methoxybenzylthio)-1-substituted pyrrolidinecarboxylic acid is reported. At each step, practically all compounds were obtained in crystalline form by simple procedure without column chromatography. These compounds are versatile side-chain precursors to carbapenem antibiotics.Keywords
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