Electrophoretic Studies on Serum and Plasma of Control and Vitamin Deficient Monkeys.

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Abstract
The plasma or serum proteins of rhesus monkeys maintained on various vit. -deficient diets were studied by chemical and by electrophoretic analysis. Partial or complete deficiency of vit. B6 resulted in hypoalbumi-nemia and a significant increase in the gamma globulin component. On a niacin-deficient diet 2 monkeys developed a lowered albumin and an increase in the gamma globulin. A low choline diet led to a decrease in the albumin and to an increase in the beta globulin. The addition of 1% cholesterol to the diet of control or vit. B6-deficient monkeys produced an increase in the alpha-3 component. The electrophoretic composition of the plasma did not appear to be altered by a state of early chronic scurvy. The mobilities of the plasma components appeared to be increased by an ascorbic acid deficient diet but were unaffected by the other regimens.