Reversal of electronic effects between inter- and intra-molecular Michael addition reactions

Abstract
Measurement of the rates of cyclisation of (E)-2-methyl-3-oxo-5-phenylpent-4-en-2-ol and its p-methoxy-derivative in trifluoroacetic acid, together with the rates of the reverse reaction, indicates an influence of stereoelectronic origin which is not present in intermolecular Michael additions.

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