Bacteriophage Grouping ofPseudomonas Aeruginosa: With Special Emphasis on Lysotypes Occurring in Infected Burns

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Abstract
Six groupings of 21 bacteriophages recovered from sewage and previously lysogenic organisms were used to detect lytic susceptibility of Pseudomonas aeruginosa isolates from burns and other infections. These bacteriophages all yielded reproducible patterns in different tests. Group 2, 3, 7 pseudomonad phage types were most commonly isolated in all burn infections. Group 16 included pseudomonad lysotype 16,95,113 as the agent responsible for the majority of septicemias in this unit. There seemed to be no particular group or phage type associated consistently with the fulminating septicopyemic state invariably fatal in burns. In no instance was the initial septicemic phage type supplanted by a different phage type during the burn patient''s clinical course. Fifteen pseudomonads of the National Institutes of Health from various sources that were demonstrated to be distinct serotypes, based on O and h antigens, were observed to have 15 separate patterns of phage types. Based on this, the phages used seem to be adequate to cover the pseudomonad disease spectrum of burns and other infections.

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