A NEW ANTIBIOTIC, GATAVALIN

Abstract
Gatavalin, a new peptide antibiotic, was isolated from cells of Bacillus polymyxa var. colistinus KOYAMA. The antimicrobial spectrum of this antibiotic is characterized by activity against gram-positive bacteria, mycobacteria, yeasts and molds. This antibiotic was named gatavalin because it contains glutamic acid, aspartic acid, threonine, alanine and valine. The isolation, purification, physico-chemical and biological properties of gatavalin are described, and the relationship with other colistinus peptides, colistin and jolipeptin, is discussed.

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