One pot synthesis of nitrogen-containing polycyclic δ-lactones by double nucleophilic addition of bis(trimethylsilyl)ketene acetals to pyridinesAll new compounds described in this paper were fully characterized by 200 and 400 MHz 1H NMR, 50 or 100 MHz 13C NMR, mass spectrometry and/or elemental analyses.
- 28 March 2002
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 9,p. 940-941
- https://doi.org/10.1039/b201780f
Abstract
Pyridine and bis(TMS)ketene acetals (TMS = trimethylsilyl) react successively with methylchloroformate and iodine (or peracids) to give, via functionalized dihydropyridines, bicyclic nitrogen-containing lactones which have been characterized by X-ray crystallography.This publication has 2 references indexed in Scilit:
- Asymmetric Synthesis of (+)-DeoxoprosopinineThe Journal of Organic Chemistry, 2001
- Regiospecific Synthesis of 4-(2-Oxoalkyl)pyridinesOrganic Letters, 2001