Thrombotic microangiopathy in a patient with chronic myelocytic leukaemia treated with α-interferon
Open Access
- 1 October 1999
- journal article
- case report
- Published by Oxford University Press (OUP) in Nephrology Dialysis Transplantation
- Vol. 14 (10) , 2469-2471
- https://doi.org/10.1093/ndt/14.10.2469
Abstract
Adverse effects of interferon (IFN) therapy on the kidney are proteinuria, rarely nephrotic syndrome, and renal failure [1–7]. Two forms of renal failure have been described: an acute form, i.e. acute interstitial nephritis or an acute tubular necrosis, occasionally associated with minimal-change nephropathy [2] or chronic progressive renal failure, usually thrombotic microangiopathy [3–7], potentially progressing to end-stage renal failure (ESRF).Keywords
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