Osmotic Regulation of theEscherichia coli bdm(Biofilm-Dependent Modulation) Gene by the RcsCDB His-Asp Phosphorelay

Abstract
The RcsCDB His-Asp phosphorelay is shown to positively regulate the bdm (biofilm-dependent modulation) and sra (stationary-phase-induced ribosome-associated protein) genes in Escherichia coli. The regulation is direct and requires an RcsB box next to the bdm −35 element. In addition, bdm is shown to be activated by osmotic shock in an Rcs-dependent way.