Attempts at chemotherapy of Echinococcus multilocularis infections in rodents

Publisher Website
Google Scholar
Abstract
Attempts were made to inhibit the growth of vegetatively propagated Echinococcus multilocularis cysts in mice by using two antischistosomals, two antimalarials, two organophosphorous parasiticides, and one cytostatic, cyclophosphamide. Of these only the latter and lucanthone inhibited the growth of cysts; 7 to 14 injections of 100 mg/kg of lucanthone inhibited it by 30 to 60%. A single injection of cyclophosphamide, 200 mg/kg, 1 week after infection, inhibited the growth by 75 to 90%. This retardation was still apparent 3 months after the injection of cyclophosphamide.

This publication has 0 references indexed in Scilit: