Effects of β-Mercaptoethylamine on Growth and Radiation Sensitivity of Escherichia coli Strain 15TAU-Bar
- 1 July 1966
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 28 (3) , 708-+
- https://doi.org/10.2307/3571998
Abstract
The addition of MEA [ mercaptoethylamine] to a logarithmically growing culture of E^ coli strain 15TAU-bar results in immediate cessation of net protein but not DNA synthesis. This change in growth state appears to be the only reason for the increase in radiation resistance of the logarithmic-phase culture incubated in MEA before irradiation. Preirradiation incubation of a stationary-phase culture with MEA does not give radioprotection. Maximum protectionof stationary-phase cultures was obtained by adding MEA to the culture immediately prior to beginning irradiation. Logarithmic-phase cultures can also be protected against ionizing radiation killing if MEA is present in the cell suspension only during irradiation. This protective effect is additive with protection afforded by preirradiation incubation with MEA.This publication has 0 references indexed in Scilit: